- Sophie Ward - Helen Trent/Walker
- Sarah Tansey - Jenny Latimer/Merton
- Phil Bellamy (Mark Jordan)
- Vernon Scripps (Geoffrey Hughes)
- Mike and Tricia
- Rosie Cartwright (Vanessa Hehir)
- Steve Crane aka James Carlton
- Nick Berry
- Rob Walker (Jonathon Kerrigan)
- Craddock - Philip Franks
- Niamh Cusack - Kate Rowen
- Aislin McGuckin - Liz Merrick
- Jason Durr
- Alan & Sarah Maskell
- Fiona Dolman aka Jackie Lambert Bradley
- Tom - Ryan Early
- Kazia Pelka aka District Nurse Maggie Bolton
- Katie Rowan
- Dr Alex Ferrenby
- Stg Craddock
- Alfred no more...
- Sarah Tansey - Other Roles
- Clare Calbraith aka Dr. Tricia Summerbee
- Claude Greengrasss (Bill Maynard)
- Richard Lintern (was Ben Norton) - Other Roles